Catherine was Henry VIII's first and 'true wife,' abandoned when she was no longer any use to him. In the furore that surrounded his relationship with Anne Boleyn it was said that Catherine had been poisoned by Anne. Today, however, it is widely considered that she died of cancer, and probably from a broken heart.
"My tribulations are so great, my life so disturbed by the plans daily invented to further the king's wicked intention, the surprises which the king gives me, with certain persons of his council, are so mortal, and my treatment is what God knows, that it is enough to shorten ten lives, much more mine."
Henry did not attend Catherine's funeral, and in one last cruel act against his wife, he forbade their daughter Mary to attend.