Following the death of her father in 1439, her brother Henry in 1446 and her niece in 1448, Anne became a very wealthy heiress.
In 1434, Anne was betrothed to Richard Neville, later the Earl of Warwick, their marriage would bring together the lands of his father, along with a major proportion of the Montague inheritance via his mother. The death of Richard at Barnet in 1471, Anne's parents estates, the Beauchamp and Despenser along with their fathers estates fell to their two daughters, Isabel and Anne, the wives of George, Duke of Clarence and Richard, Duke of Gloucester respectively.
For many being an heiress was not a passport to happiness, Anne was ignored in her lifetime, she watched as her daughters fought over their inheritance each making their claim in respect of their husbands. Even in old age Anne was forced to give up much of her fortune for a few scraps Henry VII threw her way.
Anne died in 1492, who for what ever reason, didn't make herself heard in life, and in death she was destined to be a woman history has all but forgotten.